A recent study indicates that patients who stop using popular slimming jabs like Wegovy and Mounjaro can put back on reduced body mass far faster than those who end conventional diet and exercise regimens.
Findings released in a major medical journal points out that while obese individuals frequently drop a large proportion of their total mass while undergoing treatment, the mass is regained at an estimated rate of 0.8 kg per month after stopping.
"Individuals using these drugs must be aware of the danger of fast weight regain when the medication is stopped," stated expert Dr. Susan Jebb.
That rate of regain implies a return to pre-treatment weight within about a year and a half.
Weighing Approaches
The research, which reviewed dozens of studies involving thousands of participants, contrasted the outcomes of these new drugs with other pills.
The team point out that people who lose weight through lifestyle changes alone usually see a more gradual creep back—perhaps 0.1 kg a month—post-intervention.
The Reason for the Quick Rebound
Doctors believe the way of the injections accounts for the amplified weight return.
GLP-1 drugs mimic a natural hormone called glucagon-like peptide-1, which moderates hunger.
"Artificially providing GLP-1 concentrations several times higher than the body's typical production could lead to the body to produce less of its own natural GLP-1, and could diminish sensitivity to its effects," explained Dr. Adam Collins, a nutrition researcher.
"Discontinuation of this hormone supplement leads to hunger is unsuppressed, making binge eating far more likely."
A Chronic Issue?
Medical guidelines advise the jabs for people with weight-linked health risks, alongside recommended diet and exercise modifications.
Many experts contend that, due to the significant potential of relapse, the treatment should be considered ongoing.
This opinion is supported by drug manufacturers, who note that the results "emphasize the long-term character of excess weight," comparing it to managing conditions like hypertension.
Patient Accounts
Individuals who have discontinued the jabs report a intense return of cravings.
"It felt as if a trigger flipping and I was suddenly ravenous," described a patient.
The struggle is exacerbated if users have not adopted lasting lifestyle or habit changes during treatment.
Significant Adoption
Recent estimates suggest that a significant number of people in the UK have tried these injections in the past year, with demand being substantial.
- Use is more common among women than men.
- The middle-aged age group shows the highest usage rates.
- Many obtain the drugs through private prescriptions rather than the NHS.
In conclusion, experts stress that while these medications are effective agents for shedding pounds, they are not a standalone cure and long-term success likely depends on integrated lifestyle support.
